U.S. / county disease rankings
Counties with the highest cancer incidence rates (U.S.)
Among 3,132 U.S. counties with published values, the counties with the highest cancer incidence rates are Union County, FL (1,229.6, 2.71 times the U.S. rate of 453.4), Hudspeth County, TX (842.1, 1.86 times the U.S. rate of 453.4) and Dewey County, SD (713.7, 1.57 times the U.S. rate of 453.4). Values are per 100,000, age-adjusted. 1,186 of the 3,132 are significantly above the U.S. rate.
Source: NCI and CDC State Cancer Profiles, both sexes, all ages. These are county-level figures, age-adjusted as published by the source, compared with the U.S. rate. A high rate does not prove an environmental cause: age, smoking, income, access to care, screening and chance all move county rates, and small counties swing widely. Significant means the lower bound of the county’s 95 percent confidence interval is above the U.S. rate.
Top 50 U.S. counties
All cancer cancer new cases, per 100,000, age-adjusted. Showing 50 of 3,132 counties with published values.
| Rank | County | State | Value | U.S. rate | Times reference | Significant |
|---|---|---|---|---|---|---|
| 1 | Union County | FL | 1,229.6 | 453.4 | 2.71x | Significant |
| 2 | Hudspeth County | TX | 842.1 | 453.4 | 1.86x | Significant |
| 3 | Dewey County | SD | 713.7 | 453.4 | 1.57x | Significant |
| 4 | Polk County | TX | 693.1 | 453.4 | 1.53x | Significant |
| 5 | Wolfe County | KY | 674.9 | 453.4 | 1.49x | Significant |
| 6 | Haakon County | SD | 659 | 453.4 | 1.45x | Significant |
| 7 | Esmeralda County | NV | 644.9 | 453.4 | 1.42x | No |
| 8 | Briscoe County | TX | 644.4 | 453.4 | 1.42x | Significant |
| 9 | McMullen County | TX | 630.5 | 453.4 | 1.39x | No |
| 10 | Carter County | MO | 629.5 | 453.4 | 1.39x | Significant |
| 11 | Issaquena County | MS | 624 | 453.4 | 1.38x | No |
| 12 | Mahnomen County | MN | 620.8 | 453.4 | 1.37x | Significant |
| 13 | Cumberland County | KY | 619.8 | 453.4 | 1.37x | Significant |
| 14 | Powell County | KY | 619.3 | 453.4 | 1.37x | Significant |
| 15 | Livingston County | KY | 615.8 | 453.4 | 1.36x | Significant |
| 16 | Bracken County | KY | 614.7 | 453.4 | 1.36x | Significant |
| 17 | Elk County | KS | 613.5 | 453.4 | 1.35x | Significant |
| 18 | Jerauld County | SD | 612.4 | 453.4 | 1.35x | Significant |
| 19 | Sanborn County | SD | 610.1 | 453.4 | 1.35x | Significant |
| 20 | Menard County | IL | 609.9 | 453.4 | 1.35x | Significant |
| 21 | Lawrence County | AR | 608.7 | 453.4 | 1.34x | Significant |
| 22 | Lincoln County | KY | 606.1 | 453.4 | 1.34x | Significant |
| 23 | Benton County | IN | 604.8 | 453.4 | 1.33x | Significant |
| 24 | Estill County | KY | 604.5 | 453.4 | 1.33x | Significant |
| 25 | Owsley County | KY | 604.3 | 453.4 | 1.33x | Significant |
| 26 | Lincoln County | WV | 603.8 | 453.4 | 1.33x | Significant |
| 27 | Iberville Parish | LA | 603.2 | 453.4 | 1.33x | Significant |
| 28 | Clay County | WV | 603 | 453.4 | 1.33x | Significant |
| 29 | Traverse County | MN | 602.4 | 453.4 | 1.33x | Significant |
| 30 | Cass County | IA | 601.4 | 453.4 | 1.33x | Significant |
| 31 | Fountain County | IN | 599.7 | 453.4 | 1.32x | Significant |
| 32 | Carter County | KY | 597.9 | 453.4 | 1.32x | Significant |
| 33 | Clay County | KY | 596.7 | 453.4 | 1.32x | Significant |
| 34 | Covington city | VA | 595 | 453.4 | 1.31x | Significant |
| 35 | Quitman County | MS | 594.5 | 453.4 | 1.31x | Significant |
| 36 | Knox County | KY | 593.8 | 453.4 | 1.31x | Significant |
| 37 | Edwards County | TX | 593.5 | 453.4 | 1.31x | No |
| 38 | Rockcastle County | KY | 591.6 | 453.4 | 1.3x | Significant |
| 39 | Pocahontas County | IA | 591 | 453.4 | 1.3x | Significant |
| 40 | Worth County | MO | 589.6 | 453.4 | 1.3x | Significant |
| 41 | Covington County | MS | 589.3 | 453.4 | 1.3x | Significant |
| 42 | Greenwood County | KS | 588.8 | 453.4 | 1.3x | Significant |
| 43 | Fulton County | KY | 587.8 | 453.4 | 1.3x | Significant |
| 44 | Poinsett County | AR | 587.7 | 453.4 | 1.3x | Significant |
| 45 | Cameron Parish | LA | 587.2 | 453.4 | 1.3x | Significant |
| 46 | Floyd County | KY | 587.2 | 453.4 | 1.3x | Significant |
| 47 | Faulk County | SD | 586.2 | 453.4 | 1.29x | Significant |
| 48 | Trousdale County | TN | 585.1 | 453.4 | 1.29x | Significant |
| 49 | Norman County | MN | 583.7 | 453.4 | 1.29x | Significant |
| 50 | Montour County | PA | 582.1 | 453.4 | 1.28x | Significant |