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U.S. / county disease rankings

Counties with the highest cancer incidence rates (U.S.)

Among 3,132 U.S. counties with published values, the counties with the highest cancer incidence rates are Union County, FL (1,229.6, 2.71 times the U.S. rate of 453.4), Hudspeth County, TX (842.1, 1.86 times the U.S. rate of 453.4) and Dewey County, SD (713.7, 1.57 times the U.S. rate of 453.4). Values are per 100,000, age-adjusted. 1,186 of the 3,132 are significantly above the U.S. rate.

Source: NCI and CDC State Cancer Profiles, both sexes, all ages. These are county-level figures, age-adjusted as published by the source, compared with the U.S. rate. A high rate does not prove an environmental cause: age, smoking, income, access to care, screening and chance all move county rates, and small counties swing widely. Significant means the lower bound of the county’s 95 percent confidence interval is above the U.S. rate.

Top 50 U.S. counties

All cancer cancer new cases, per 100,000, age-adjusted. Showing 50 of 3,132 counties with published values.

Counties with the highest cancer incidence rates (U.S.)
RankCountyStateValueU.S. rateTimes referenceSignificant
1Union CountyFL1,229.6453.42.71xSignificant
2Hudspeth CountyTX842.1453.41.86xSignificant
3Dewey CountySD713.7453.41.57xSignificant
4Polk CountyTX693.1453.41.53xSignificant
5Wolfe CountyKY674.9453.41.49xSignificant
6Haakon CountySD659453.41.45xSignificant
7Esmeralda CountyNV644.9453.41.42xNo
8Briscoe CountyTX644.4453.41.42xSignificant
9McMullen CountyTX630.5453.41.39xNo
10Carter CountyMO629.5453.41.39xSignificant
11Issaquena CountyMS624453.41.38xNo
12Mahnomen CountyMN620.8453.41.37xSignificant
13Cumberland CountyKY619.8453.41.37xSignificant
14Powell CountyKY619.3453.41.37xSignificant
15Livingston CountyKY615.8453.41.36xSignificant
16Bracken CountyKY614.7453.41.36xSignificant
17Elk CountyKS613.5453.41.35xSignificant
18Jerauld CountySD612.4453.41.35xSignificant
19Sanborn CountySD610.1453.41.35xSignificant
20Menard CountyIL609.9453.41.35xSignificant
21Lawrence CountyAR608.7453.41.34xSignificant
22Lincoln CountyKY606.1453.41.34xSignificant
23Benton CountyIN604.8453.41.33xSignificant
24Estill CountyKY604.5453.41.33xSignificant
25Owsley CountyKY604.3453.41.33xSignificant
26Lincoln CountyWV603.8453.41.33xSignificant
27Iberville ParishLA603.2453.41.33xSignificant
28Clay CountyWV603453.41.33xSignificant
29Traverse CountyMN602.4453.41.33xSignificant
30Cass CountyIA601.4453.41.33xSignificant
31Fountain CountyIN599.7453.41.32xSignificant
32Carter CountyKY597.9453.41.32xSignificant
33Clay CountyKY596.7453.41.32xSignificant
34Covington cityVA595453.41.31xSignificant
35Quitman CountyMS594.5453.41.31xSignificant
36Knox CountyKY593.8453.41.31xSignificant
37Edwards CountyTX593.5453.41.31xNo
38Rockcastle CountyKY591.6453.41.3xSignificant
39Pocahontas CountyIA591453.41.3xSignificant
40Worth CountyMO589.6453.41.3xSignificant
41Covington CountyMS589.3453.41.3xSignificant
42Greenwood CountyKS588.8453.41.3xSignificant
43Fulton CountyKY587.8453.41.3xSignificant
44Poinsett CountyAR587.7453.41.3xSignificant
45Cameron ParishLA587.2453.41.3xSignificant
46Floyd CountyKY587.2453.41.3xSignificant
47Faulk CountySD586.2453.41.29xSignificant
48Trousdale CountyTN585.1453.41.29xSignificant
49Norman CountyMN583.7453.41.29xSignificant
50Montour CountyPA582.1453.41.28xSignificant

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