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Madison County, Missouri: environmental and disease records

Cancer mortality in Madison County is 214.8 deaths per 100,000 people per year against a U.S. rate of 143.2, a statistically significant excess. The strongest disease signals are Lung & bronchus deaths at 2.2 times the U.S. rate. Federal databases place 89 regulated facilities, sites and hazards inside the county, led by NPDES wastewater discharge permit (45), Industrial wastewater discharge (14), Air permit holder (minor source) (11). EPA AirToxScreen estimates a lifetime cancer risk from outdoor air toxics of 30 in a million, driven mainly by formaldehyde.

Rates are age-adjusted per 100,000 people. A cancer signal is marked significant when the lower bound of its 95 percent confidence interval is above the U.S. rate. Facility counts use active federal records located inside the county boundary. Approximate county center: 37.473, -90.3456.

How this county ranks in Missouri

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Cancer deaths and new cases versus the United States

Source: NCI and CDC State Cancer Profiles, both sexes, all ages. Sorted by the ratio of the county rate to the U.S. rate.

Cancer rates for Madison County compared with the United States
Cancer	Measure	County rate	U.S. rate	Times U.S.	95% interval	Years
Lung & bronchus	Deaths	66.9	30.2	2.22xSignificant	51.2 to 86.5	2020-2024
Lung & bronchus	New cases	110.2	51.8	2.13xSignificant	89.6 to 134.8	2019-2023
Kidney & renal pelvis	New cases	28.8	17.9	1.61x	17.8 to 44.4	2019-2023
All cancer	Deaths	214.8	143.2	1.5xSignificant	185.1 to 248.5	2020-2024
All cancer	New cases	553	453.4	1.22xSignificant	502.7 to 607.4	2019-2023
Melanoma of the skin	New cases	28.9	23.8	1.21x	17.3 to 45.3	2019-2023
Bladder	New cases	22	18.7	1.18x	13.4 to 34.7	2019-2023
Non-Hodgkin lymphoma	New cases	19.3	18.5	1.04x	10.7 to 32.5	2019-2023

Mortality measures versus the U.S. county median

Source: County Health Rankings, built from CDC National Vital Statistics System death records. The comparison value is the median of all U.S. counties.

Mortality measures for Madison County
Measure	County	U.S. median	Difference	Unit
Premature death	11,891	9,842.6	+21%	years of life lost before age 75 per 100,000
Life expectancy	72.3	75.3	-4%	years
Child mortality	n/a	59.8	n/a	deaths under age 18 per 100,000
Infant mortality	n/a	6.2	n/a	deaths under age 1 per 1,000 live births
Injury deaths	89	96.9	-8%	deaths per 100,000
Drug overdose deaths	40	28.6	+40%	deaths per 100,000

Air toxics and air quality

EPA AirToxScreen 2020

Lifetime cancer risk from outdoor air toxics: 30 in a million. EPA treats 100 in a million as the upper end of acceptable risk and 1 in a million as the goal.

Formaldehyde18.66 per million
Carbon Tetrachloride2.91 per million
Acetaldehyde1.8 per million
Benzene0.76 per million

EPA Air Quality Index

No EPA air quality monitor reports daily AQI for this county.

Regulated facilities, sites and hazards by type

89 active records inside the county from EPA ECHO, TRI, Superfund, Brownfields, NPDES, EIA, FAA, FRA and corrections data.

NPDES wastewater discharge permit45
Industrial wastewater discharge14
Air permit holder (minor source)11
Brownfield property6
Small hazardous waste generator4
Public airport2
Major air pollution source1
Gas station (mapped facility)1
Heliport1
Gas power plant1
Superfund (NPL) site1
Toxic chemical release facility (TRI)1
Wastewater plant (mapped facility)1

Highest-severity records

The 25 records with the highest Envyrofax severity in the county, with the agency identifier to cite in a records request.

Madison County Mines, Fredericktown
Superfund (NPL) site. Hazard Ranking System score 58.4. NPL Site.
EPA site ID MOD098633415 (U.S. EPA Superfund (SEMS/NPL)) Agency record
Severity 10
Missouri Cobalt, Fredericktown
Toxic chemical release facility (TRI). Chemicals: Lead, Copper, Nickel, Cobalt. Reports carcinogens. 1,634,344 lbs released over 5 years.
TRI facility ID 6364WMSSRC15CUN (U.S. EPA Toxics Release Inventory)
Severity 9.3
Mississippi River Transmission, Fredericktown
Major air pollution source.
EPA FRS registry ID 110017994492 (U.S. EPA ECHO) Agency record
Severity 6.5
Madison County Mines, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110009339288 (U.S. EPA ECHO) Agency record
Severity 6
Mississippi River Transmission, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110017994492 (U.S. EPA ECHO) Agency record
Severity 6
Marquand Pws, Marquand
NPDES wastewater discharge permit. Penalties $6,000.
EPA FRS registry ID 110009869712 (U.S. EPA ECHO) Agency record
Severity 5.5
Motor City Wwtf, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110064297283 (U.S. EPA ECHO) Agency record
Severity 4.5
Fredericktown Pws-Fredericktown - Treatment Plant, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110006731206 (U.S. EPA ECHO) Agency record
Severity 3.8
Mill Creek Mhp Wwtp, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110029519741 (U.S. EPA ECHO) Agency record
Severity 3.8
Mpc 1002 Wwtf, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110071711342 (U.S. EPA ECHO) Agency record
Severity 3.5
Fredericktown Energy Center, Fredericktown
Gas power plant.
Record ID 57946 (U.S. Energy Information Administration)
Severity 3
Madison Medical Center, Fredericktown
Brownfield property.
EPA FRS registry ID 110007105587 (U.S. EPA Brownfields (ACRES)) Agency record
Severity 3
Fredericktown Greenway Development, Fredericktown
Brownfield property.
EPA FRS registry ID 110015333646 (U.S. EPA Brownfields (ACRES)) Agency record
Severity 3
Mine La Motte School, Fredericktown
Brownfield property.
EPA FRS registry ID 110038756021 (U.S. EPA Brownfields (ACRES)) Agency record
Severity 3
Mill Creek School, Fredericktown
Brownfield property.
EPA FRS registry ID 110038756030 (U.S. EPA Brownfields (ACRES)) Agency record
Severity 3
Kris Corner Beauty Shop, Fredericktown
Brownfield property.
EPA FRS registry ID 110040720565 (U.S. EPA Brownfields (ACRES)) Agency record
Severity 3
Old Tavern Hotel/Ben Franklin Store, Fredericktown
Brownfield property.
EPA FRS registry ID 110040720583 (U.S. EPA Brownfields (ACRES)) Agency record
Severity 3
Faith Foundations Children'S Home, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110017982708 (U.S. EPA ECHO) Agency record
Severity 3
Fredericktown Wwtp, Fredericktown
Industrial wastewater discharge. Violation Identified.
NPDES permit MO0028690: (U.S. EPA NPDES)
Severity 2.8
Mpc 1002 Wwtf, Fredericktown
Industrial wastewater discharge. Significant/Category I Noncompliance.
NPDES permit MO0055956: (U.S. EPA NPDES)
Severity 2.8
Deguire Subdivision, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110009711188 (U.S. EPA ECHO) Agency record
Severity 2.8
Pinecrest Camp Wwtf, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110064335358 (U.S. EPA ECHO) Agency record
Severity 2.3
Tab'S Meat Processing, Fredericktown
NPDES wastewater discharge permit.
EPA FRS registry ID 110071711242 (U.S. EPA ECHO) Agency record
Severity 2.3
S-F Scout Ranch Water Treatment Plant, Knob Lick
NPDES wastewater discharge permit.
EPA FRS registry ID 110009888167 (U.S. EPA ECHO) Agency record
Severity 2
A Paul Vance Fredericktown Rgnl, Fredericktown
Public airport. O.
Record ID H88 (FAA / U.S. DOT)
Severity 2

Correctional facilities

Prisons, jails and corrections operations with an EPA facility record, and the drinking water and wastewater compliance attached to them.

No correctional facility with an EPA record is located in this county.

Discovery / public records

Records to request for Madison County

Missouri state cancer registry
Cancer incidence counts by census tract or ZIP code, by cancer type and year (de-identified). Any cancer cluster inquiries or investigations in Madison County, and their findings.
Missouri vital statistics office
Death certificate counts by cause of death and residence tract or ZIP code, and the years behind the mortality measures above.
Missouri health department, environmental epidemiology
Health consultations or assessments by ATSDR or the state health department covering the county, and any exposure investigations.
Missouri environmental agency and the U.S. EPA regional office
Compliance history, inspection reports, notices of violation, penalties and enforcement actions for each facility above, cited by EPA FRS registry ID.
Missouri drinking water program
Violation notices, sampling results and sanitary surveys for the public water systems serving the county, including any system serving a correctional facility.
Department of corrections or county sheriff
Water testing, grievances and environmental health inspections for the correctional facilities listed above.

Each Envyrofax address report includes a printable records request worksheet with the custodian and the exact request wording per finding.

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