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Madison County, Illinois: environmental and disease records

Cancer mortality in Madison County is 166.6 deaths per 100,000 people per year against a U.S. rate of 143.2, a statistically significant excess. The strongest disease signals are Melanoma of the skin deaths at 1.6 times the U.S. rate and Lung & bronchus deaths at 1.5 times the U.S. rate. Federal databases place 1,784 regulated facilities, sites and hazards inside the county, led by NPDES wastewater discharge permit (421), Air permit holder (minor source) (342), Industrial wastewater discharge (309). One correctional facility operates in the county. EPA AirToxScreen estimates a lifetime cancer risk from outdoor air toxics of 30 in a million, driven mainly by formaldehyde.

Rates are age-adjusted per 100,000 people. A cancer signal is marked significant when the lower bound of its 95 percent confidence interval is above the U.S. rate. Facility counts use active federal records located inside the county boundary. Approximate county center: 38.8228, -89.8559.

How this county ranks in Illinois

Cancer deaths and new cases versus the United States

Source: NCI and CDC State Cancer Profiles, both sexes, all ages. Sorted by the ratio of the county rate to the U.S. rate.

Cancer rates for Madison County compared with the United States
CancerMeasureCounty rateU.S. rateTimes U.S.95% intervalYears
Melanoma of the skinDeaths3.221.6xSignificant2.4 to 4.22020-2024
Lung & bronchusDeaths43.930.21.45xSignificant40.9 to 47.12020-2024
Lung & bronchusNew cases74.351.81.43xSignificant70.3 to 78.42019-2023
Kidney & renal pelvisNew cases25.617.91.43xSignificant23.1 to 28.22019-2023
EsophagusDeaths4.93.71.32xSignificant4 to 6.12020-2024
Melanoma of the skinNew cases28.723.81.21xSignificant26 to 31.52019-2023
Brain & nervous systemNew cases7.36.21.18x5.9 to 8.92019-2023
All cancerDeaths166.6143.21.16xSignificant160.6 to 172.92020-2024
Brain & nervous systemDeaths5.14.41.16x4.1 to 6.42020-2024
BladderNew cases21.518.71.15xSignificant19.4 to 23.82019-2023
Kidney & renal pelvisDeaths3.93.41.15x3 to 52020-2024
EsophagusNew cases5.24.61.13x4.2 to 6.42019-2023
LeukemiaDeaths6.45.71.12x5.3 to 7.82020-2024
BladderDeaths4.64.11.12x3.7 to 5.82020-2024
All cancerNew cases502.1453.41.11xSignificant491.3 to 513.22019-2023
LeukemiaNew cases15.514.51.07x13.6 to 17.52019-2023
PancreasNew cases14.713.91.06x12.9 to 16.62019-2023
PancreasDeaths11.911.31.05x10.3 to 13.72020-2024
Liver & bile ductDeaths6.96.61.05x5.7 to 8.22020-2024
Liver & bile ductNew cases8.98.71.02x7.5 to 10.42019-2023
Childhood cancer (under 15)New cases16.716.41.02x11.8 to 22.82019-2023
Non-Hodgkin lymphomaNew cases18.618.51.01x16.6 to 20.92019-2023
Non-Hodgkin lymphomaDeaths4.84.81x3.8 to 5.92020-2024
StomachDeaths2.72.71x2 to 3.62020-2024
ThyroidNew cases13131x11.1 to 15.12019-2023
StomachNew cases66.60.91x4.9 to 7.42019-2023

Mortality measures versus the U.S. county median

Source: County Health Rankings, built from CDC National Vital Statistics System death records. The comparison value is the median of all U.S. counties.

Mortality measures for Madison County
MeasureCountyU.S. medianDifferenceUnit
Premature death9,1599,842.6-7%years of life lost before age 75 per 100,000
Life expectancy75.475.3+0%years
Child mortality38.459.8-36%deaths under age 18 per 100,000
Infant mortality6.46.2+3%deaths under age 1 per 1,000 live births
Injury deaths10796.9+10%deaths per 100,000
Drug overdose deaths39.928.6+40%deaths per 100,000

Air toxics and air quality

EPA AirToxScreen 2020

Lifetime cancer risk from outdoor air toxics: 30 in a million. EPA treats 100 in a million as the upper end of acceptable risk and 1 in a million as the goal.

  • Formaldehyde20.59 per million
  • Carbon Tetrachloride2.96 per million
  • Acetaldehyde1.91 per million
  • Naphthalene1.53 per million

EPA Air Quality Index 2025

Monitored on 365 days: 191 good, 4 unhealthy for sensitive groups or worse. Median AQI 49, peak 260.

Regulated facilities, sites and hazards by type

1,784 active records inside the county from EPA ECHO, TRI, Superfund, Brownfields, NPDES, EIA, FAA, FRA and corrections data.

  • NPDES wastewater discharge permit421
  • Air permit holder (minor source)342
  • Industrial wastewater discharge309
  • Rail grade crossing292
  • Gas station (mapped facility)97
  • Brownfield property58
  • Auto repair or body shop (mapped facility)54
  • Small hazardous waste generator37
  • Large hazardous waste generator30
  • Toxic chemical release facility (TRI)27
  • TRI reporting facility25
  • Major air pollution source20
  • Combined sewer overflow outfall13
  • Large greenhouse gas emitter10
  • Hazardous waste transporter7
  • Wastewater plant (mapped facility)7
  • EPA air quality monitor6
  • Public airport5
  • Heliport5
  • Dry cleaner (mapped facility)3
  • Scrapyard (mapped facility)3
  • Superfund (NPL) site3
  • Gas power plant2
  • Oil-fired power plant2
  • Airfield1
  • Commercial airport1
  • Correctional facility (prison or jail)1
  • Landfill (mapped facility)1
  • Other power plant1
  • Solar power plant1

Highest-severity records

The 25 records with the highest Envyrofax severity in the county, with the agency identifier to cite in a records request.

  1. Phillips 66 Company, Roxana

    TRI reporting facility. Penalties $125,865.

    EPA FRS registry ID 110041962873 (U.S. EPA ECHO) Agency record

    Severity 10
  2. Jennison-Wright Corporation, Granite City

    Superfund (NPL) site. Hazard Ranking System score 40.3. NPL Site.

    EPA site ID ILD006282479 (U.S. EPA Superfund (SEMS/NPL)) Agency record

    Severity 10
  3. Chemetco, Hartford

    Superfund (NPL) site. Hazard Ranking System score 30. NPL Site.

    EPA site ID ILD048843809 (U.S. EPA Superfund (SEMS/NPL)) Agency record

    Severity 10
  4. NL Industries/Taracorp Lead Smelter, Granite City

    Superfund (NPL) site. Hazard Ranking System score 38.1. NPL Site.

    EPA site ID ILD096731468 (U.S. EPA Superfund (SEMS/NPL)) Agency record

    Severity 10
  5. Wood River Refinery, Roxana

    Toxic chemical release facility (TRI). Chemicals: Nitrate compounds (water dissociable; reportable only when in aqueous solution), Sulfuric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size), n-Hexane, Benzene and 4 more. Reports carcinogens. 13,114,349 lbs released over 5 years.

    TRI facility ID 62084SHLLLRTE11 (U.S. EPA Toxics Release Inventory)

    Severity 10
  6. U.S. Steel Granite City Works, Granite City

    Toxic chemical release facility (TRI). Chemicals: Zinc compounds, Manganese And Manganese Compounds, Nitrate compounds (water dissociable; reportable only when in aqueous solution), Lead And Lead Compounds and 4 more. Reports carcinogens. 7,173,985 lbs released over 5 years.

    TRI facility ID 62040GRNTC20THS (U.S. EPA Toxics Release Inventory)

    Severity 9.8
  7. Phillips 66 Company, Hartford

    TRI reporting facility. Penalties $50,000.

    EPA FRS registry ID 110010829871 (U.S. EPA ECHO) Agency record

    Severity 9.7
  8. Granite City Works Of United States Steel Corp, Granite City

    TRI reporting facility.

    EPA FRS registry ID 110018406679 (U.S. EPA ECHO) Agency record

    Severity 9.4
  9. Gateway Energy & Coke Co, Granite City

    Toxic chemical release facility (TRI). Chemicals: Hydrochloric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size), Sulfuric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size), Hydrogen fluoride, Lead And Lead Compounds and 2 more. Reports carcinogens. 526,040 lbs released over 5 years.

    TRI facility ID 6204WGTWYN2585E (U.S. EPA Toxics Release Inventory)

    Severity 8.9
  10. Wieland Rolled Products N.A. - East Alton Casting P, East Alton

    Toxic chemical release facility (TRI). Chemicals: Zinc (fume or dust), Copper And Copper Compounds, Nickel, Zinc compounds and 3 more. Reports carcinogens. 310,067 lbs released over 5 years.

    TRI facility ID 62024LNCRPLEWIS (U.S. EPA Toxics Release Inventory)

    Severity 8.7
  11. Precoat Metals, Granite City

    Toxic chemical release facility (TRI). Chemicals: Certain glycol ethers, n-Butyl alcohol, 1,2,4-Trimethylbenzene, Xylene (mixed isomers) and 4 more. Reports carcinogens. 138,299 lbs released over 5 years.

    TRI facility ID 62040PRCTM25NOR (U.S. EPA Toxics Release Inventory)

    Severity 8.4
  12. Olin Winchester Llc, East Alton

    TRI reporting facility. Penalties $962,985.

    EPA FRS registry ID 110000438688 (U.S. EPA ECHO) Agency record

    Severity 8.4
  13. Green Plains Madison Llc, Madison

    Toxic chemical release facility (TRI). Chemicals: n-Hexane, Acetaldehyde, Formic acid, Formaldehyde and 4 more. Reports carcinogens. 50,548 lbs released over 5 years.

    TRI facility ID 6206WBNGBN395BI (U.S. EPA Toxics Release Inventory)

    Severity 8.1
  14. Olin Winchester Llc Main Plant, East Alton

    Toxic chemical release facility (TRI). Chemicals: Nitrate compounds (water dissociable; reportable only when in aqueous solution), Ethylene glycol, Zinc compounds, Copper And Copper Compounds and 4 more. Reports carcinogens. 47,566 lbs released over 5 years.

    TRI facility ID 62024LNCRPSHAMR (U.S. EPA Toxics Release Inventory)

    Severity 8.1
  15. Amsted Rail Co Inc, Granite City

    Toxic chemical release facility (TRI). Chemicals: Manganese compounds, Zinc compounds, Naphthalene, Phenol and 2 more. Reports carcinogens. 33,709 lbs released over 5 years.

    TRI facility ID 62040MRCNS1700W (U.S. EPA Toxics Release Inventory)

    Severity 8
  16. Alton Steel Inc, Alton

    Toxic chemical release facility (TRI). Chemicals: Zinc compounds, Manganese And Manganese Compounds, Lead And Lead Compounds, Lead compounds and 3 more. Reports carcinogens. 24,158 lbs released over 5 years.

    TRI facility ID 62002LCLDSCUTST (U.S. EPA Toxics Release Inventory)

    Severity 7.9
  17. Phillips 66 Terminal, Hartford

    Toxic chemical release facility (TRI). Chemicals: Xylene (mixed isomers), Toluene, 1,2,4-Trimethylbenzene, n-Hexane and 4 more. Reports carcinogens. 22,418 lbs released over 5 years.

    TRI facility ID 62048CNCNC2150S (U.S. EPA Toxics Release Inventory)

    Severity 7.8
  18. Green Plains Madison Llc, Madison

    TRI reporting facility.

    EPA FRS registry ID 110056955120 (U.S. EPA ECHO) Agency record

    Severity 7.7
  19. Phillips 66 Company, Roxana

    Major air pollution source. Penalties $125,865.

    EPA FRS registry ID 110041962873 (U.S. EPA ECHO) Agency record

    Severity 7.5
  20. Midwest Metal Coatings, Granite City

    Toxic chemical release facility (TRI). Chemicals: Certain glycol ethers, n-Butyl alcohol, 1,2,4-Trimethylbenzene, Naphthalene. Reports carcinogens. 7,283 lbs released over 5 years.

    TRI facility ID 62040MDWST9KONZ (U.S. EPA Toxics Release Inventory)

    Severity 7.5
  21. The Premcor Refining Group, Inc. - Valero Terminaling And Distribution Company, Hartford

    TRI reporting facility.

    EPA FRS registry ID 110040961705 (U.S. EPA ECHO) Agency record

    Severity 7.4
  22. Wieland Rolled Products N.A. - East Alton Main Plan, East Alton

    Toxic chemical release facility (TRI). Chemicals: Zinc compounds, Copper, Nickel, Chromium and 2 more. Reports carcinogens. 5,942 lbs released over 5 years.

    TRI facility ID 62024BRSSM427NS (U.S. EPA Toxics Release Inventory)

    Severity 7.4
  23. Alton Steel Inc, Alton

    TRI reporting facility.

    EPA FRS registry ID 110000438679 (U.S. EPA ECHO) Agency record

    Severity 7.4
  24. Heidtman Steel Products Inc., Granite City

    Toxic chemical release facility (TRI). Chemicals: Hydrochloric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size), Manganese, Nickel, Chromium and 1 more. Reports carcinogens. 4,677 lbs released over 5 years.

    TRI facility ID 62040HDTMN10NOR (U.S. EPA Toxics Release Inventory)

    Severity 7.3
  25. Spectrulite Consortium Incorporated, Madison

    TRI reporting facility.

    EPA FRS registry ID 110000438811 (U.S. EPA ECHO) Agency record

    Severity 7

Correctional facilities

Prisons, jails and corrections operations with an EPA facility record, and the drinking water and wastewater compliance attached to them.

  • Melvin Price Locks And Dam Design Deficiency Corrections Project, Alton

    EPA FRS registry ID
    110071501155
    Wastewater permit
    Yes

    EPA detailed facility report

Discovery / public records

Records to request for Madison County

  • Illinois state cancer registry

    Cancer incidence counts by census tract or ZIP code, by cancer type and year (de-identified). Any cancer cluster inquiries or investigations in Madison County, and their findings.

  • Illinois vital statistics office

    Death certificate counts by cause of death and residence tract or ZIP code, and the years behind the mortality measures above.

  • Illinois health department, environmental epidemiology

    Health consultations or assessments by ATSDR or the state health department covering the county, and any exposure investigations.

  • Illinois environmental agency and the U.S. EPA regional office

    Compliance history, inspection reports, notices of violation, penalties and enforcement actions for each facility above, cited by EPA FRS registry ID.

  • Illinois drinking water program

    Violation notices, sampling results and sanitary surveys for the public water systems serving the county, including any system serving a correctional facility.

  • Department of corrections or county sheriff

    Water testing, grievances and environmental health inspections for the correctional facilities listed above.

Each Envyrofax address report includes a printable records request worksheet with the custodian and the exact request wording per finding.