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Florence County, South Carolina: environmental and disease records

Cancer mortality in Florence County is 158.5 deaths per 100,000 people per year against a U.S. rate of 143.2, a statistically significant excess. The strongest disease signals are Lung & bronchus deaths at 1.3 times the U.S. rate. Federal databases place 641 regulated facilities, sites and hazards inside the county, led by NPDES wastewater discharge permit (302), Rail grade crossing (94), Gas station (mapped facility) (53). EPA AirToxScreen estimates a lifetime cancer risk from outdoor air toxics of 30 in a million, driven mainly by formaldehyde.

Rates are age-adjusted per 100,000 people. A cancer signal is marked significant when the lower bound of its 95 percent confidence interval is above the U.S. rate. Facility counts use active federal records located inside the county boundary. Approximate county center: 34.0419, -79.7529.

How this county ranks in South Carolina

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Cancer deaths and new cases versus the United States

Source: NCI and CDC State Cancer Profiles, both sexes, all ages. Sorted by the ratio of the county rate to the U.S. rate.

Cancer rates for Florence County compared with the United States
CancerMeasureCounty rateU.S. rateTimes U.S.95% intervalYears
StomachDeaths3.82.71.41x2.6 to 5.52020-2024
Kidney & renal pelvisDeaths4.73.41.38x3.3 to 6.42020-2024
EsophagusNew cases6.34.61.37xSignificant4.8 to 8.32019-2023
Lung & bronchusDeaths39.730.21.31xSignificant35.6 to 442020-2024
Kidney & renal pelvisNew cases22.517.91.26xSignificant19.4 to 262019-2023
Lung & bronchusNew cases63.751.81.23xSignificant58.5 to 69.22019-2023
EsophagusDeaths4.13.71.11x2.9 to 5.82020-2024
All cancerDeaths158.5143.21.11xSignificant150.2 to 167.22020-2024
StomachNew cases76.61.06x5.4 to 92019-2023
PancreasNew cases14.613.91.05x12.2 to 17.52019-2023
All cancerNew cases472453.41.04xSignificant457.3 to 4872019-2023
BladderNew cases18.818.71.01x16 to 21.92019-2023
Brain & nervous systemNew cases6.16.20.98x4.4 to 8.22019-2023
PancreasDeaths11.111.30.98x8.9 to 13.52020-2024
Non-Hodgkin lymphomaDeaths4.64.80.96x3.3 to 6.42020-2024
Liver & bile ductNew cases7.98.70.91x6.2 to 9.92019-2023
Non-Hodgkin lymphomaNew cases16.318.50.88x13.7 to 19.32019-2023
Liver & bile ductDeaths5.86.60.88x4.4 to 7.62020-2024
LeukemiaNew cases12.514.50.86x10.2 to 15.12019-2023
BladderDeaths3.54.10.85x2.4 to 5.12020-2024
Brain & nervous systemDeaths3.14.40.7x2 to 4.62020-2024
LeukemiaDeaths3.95.70.68x2.7 to 5.52020-2024
ThyroidNew cases7.2130.55x5.3 to 9.52019-2023
Melanoma of the skinNew cases10.723.80.45x8.6 to 13.32019-2023

Mortality measures versus the U.S. county median

Source: County Health Rankings, built from CDC National Vital Statistics System death records. The comparison value is the median of all U.S. counties.

Mortality measures for Florence County
MeasureCountyU.S. medianDifferenceUnit
Premature death14,826.69,842.6+51%years of life lost before age 75 per 100,000
Life expectancy70.875.3-6%years
Child mortality101.659.8+70%deaths under age 18 per 100,000
Infant mortality11.66.2+87%deaths under age 1 per 1,000 live births
Injury deaths113.996.9+18%deaths per 100,000
Drug overdose deaths42.128.6+47%deaths per 100,000

Air toxics and air quality

EPA AirToxScreen 2020

Lifetime cancer risk from outdoor air toxics: 30 in a million. EPA treats 100 in a million as the upper end of acceptable risk and 1 in a million as the goal.

  • Formaldehyde21.45 per million
  • Carbon Tetrachloride2.94 per million
  • Acetaldehyde2.15 per million
  • Benzene0.88 per million

EPA Air Quality Index 2025

Monitored on 361 days: 235 good, 1 unhealthy for sensitive groups or worse. Median AQI 44, peak 108.

Regulated facilities, sites and hazards by type

641 active records inside the county from EPA ECHO, TRI, Superfund, Brownfields, NPDES, EIA, FAA, FRA and corrections data.

  • NPDES wastewater discharge permit302
  • Rail grade crossing94
  • Gas station (mapped facility)53
  • Air permit holder (minor source)48
  • Brownfield property33
  • Small hazardous waste generator26
  • Toxic chemical release facility (TRI)18
  • Auto repair or body shop (mapped facility)16
  • TRI reporting facility15
  • Solar power plant8
  • Major air pollution source6
  • Public airport4
  • Large hazardous waste generator4
  • Large greenhouse gas emitter3
  • Wastewater plant (mapped facility)3
  • EPA air quality monitor2
  • Scrapyard (mapped facility)2
  • Commercial airport1
  • Dry cleaner (mapped facility)1
  • Heliport1
  • Biomass power plant1

Highest-severity records

The 25 records with the highest Envyrofax severity in the county, with the agency identifier to cite in a records request.

  1. Westrock Cp, Llc - Florence Mill, Florence

    TRI reporting facility. Penalties $4,000.

    EPA FRS registry ID 110056961890 (U.S. EPA ECHO) Agency record

    Severity 10

  2. Westrock Cp Llc, Florence

    Toxic chemical release facility (TRI). Chemicals: Methanol, Manganese And Manganese Compounds, Ammonia, Hydrochloric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size) and 4 more. Reports carcinogens. 5,505,393 lbs released over 5 years.

    TRI facility ID 29502STNCNOLDGE (U.S. EPA Toxics Release Inventory)

    Severity 9.7

  3. Nan Ya Plastics Corp America, Lake City

    Toxic chemical release facility (TRI). Chemicals: Acetaldehyde, Ethylene glycol, 1,4-Dioxane, Biphenyl and 4 more. Reports carcinogens. 328,148 lbs released over 5 years.

    TRI facility ID 29560NNYPLHWY52 (U.S. EPA Toxics Release Inventory)

    Severity 8.7

  4. Nucor Corp Vulcraft Div, Florence

    Toxic chemical release facility (TRI). Chemicals: Certain glycol ethers, Manganese compounds, Manganese, Nickel compounds and 3 more. Reports carcinogens. 236,957 lbs released over 5 years.

    TRI facility ID 29501VLCRF1501W (U.S. EPA Toxics Release Inventory)

    Severity 8.6

  5. Charles Ingram Lumber Co, Effingham

    Toxic chemical release facility (TRI). Chemicals: Methanol, Formaldehyde, Lead And Lead Compounds, Lead compounds and 1 more. Reports carcinogens. 193,249 lbs released over 5 years.

    TRI facility ID 29541CHRLS4930P (U.S. EPA Toxics Release Inventory)

    Severity 8.6

  6. Patheon Api Inc., Florence

    Toxic chemical release facility (TRI). Chemicals: Methanol, Dichloromethane, Methyl tert-butyl ether, Toluene and 4 more. Reports carcinogens. 56,737 lbs released over 5 years.

    TRI facility ID 29506RCHCRBUILD (U.S. EPA Toxics Release Inventory)

    Severity 8.1

  7. Steelfab Inc, Florence

    Toxic chemical release facility (TRI). Chemicals: Xylene (mixed isomers), Manganese, Copper, Nickel and 2 more. Reports carcinogens. 31,221 lbs released over 5 years.

    TRI facility ID 29502STLFB1220S (U.S. EPA Toxics Release Inventory)

    Severity 7.9

  8. Koppers Inc. (Florence Sc), Florence

    Toxic chemical release facility (TRI). Chemicals: Creosote, Polycyclic aromatic compounds, Benzo[g,h,i]perylene. Reports carcinogens. 16,228 lbs released over 5 years.

    TRI facility ID 29503KPPRSHIGHW (U.S. EPA Toxics Release Inventory)

    Severity 7.7

  9. Patheon Api Services Inc., Florence

    Toxic chemical release facility (TRI). Chemicals: Dichloromethane, Methanol, Methyl tert-butyl ether, Toluene and 2 more. Reports carcinogens. 10,626 lbs released over 5 years.

    TRI facility ID 29501RXPHR101TE (U.S. EPA Toxics Release Inventory)

    Severity 7.6

  10. Westrock Cp, Llc - Florence Mill, Florence

    Major air pollution source. Penalties $4,000.

    EPA FRS registry ID 110056961890 (U.S. EPA ECHO) Agency record

    Severity 7.3

  11. City Of Florence Pee Dee River Wwtp, Florence

    NPDES wastewater discharge permit. Penalties $14,000.

    EPA FRS registry ID 110000544180 (U.S. EPA ECHO) Agency record

    Severity 7

  12. Lake City Waste Water Treatment Plant, Lake City

    NPDES wastewater discharge permit. Penalties $8,150.

    EPA FRS registry ID 110006623270 (U.S. EPA ECHO) Agency record

    Severity 6.8

  13. Westrock Cp, Llc - Florence Mill, Florence

    NPDES wastewater discharge permit. Penalties $4,000.

    EPA FRS registry ID 110056961890 (U.S. EPA ECHO) Agency record

    Severity 6.8

  14. Clarios Llc, Florence

    Toxic chemical release facility (TRI). Chemicals: Lead compounds, Mercury, Antimony, Arsenic. Reports carcinogens. 369 lbs released over 5 years.

    TRI facility ID 2950WJHNSN18PAP (U.S. EPA Toxics Release Inventory)

    Severity 6.5

  15. General Electric Healthcare Manufacturing Llc, Florence

    TRI reporting facility.

    EPA FRS registry ID 110002233100 (U.S. EPA ECHO) Agency record

    Severity 6.4

  16. Koppers Industries Incorporated, Florence

    TRI reporting facility.

    EPA FRS registry ID 110000492770 (U.S. EPA ECHO) Agency record

    Severity 6.4

  17. Westrock Cp, Llc - Florence Mill, Florence

    Large greenhouse gas emitter. Penalties $4,000.

    EPA FRS registry ID 110056961890 (U.S. EPA ECHO) Agency record

    Severity 6.3

  18. Charles Ingram Lumber Co Inc, Effingham

    TRI reporting facility.

    EPA FRS registry ID 110002232860 (U.S. EPA ECHO) Agency record

    Severity 6.2

  19. Nan Ya Plastics Corps, Lake City

    TRI reporting facility.

    EPA FRS registry ID 110000353965 (U.S. EPA ECHO) Agency record

    Severity 6.2

  20. Roche Carolina Incorporated, Florence

    TRI reporting facility.

    EPA FRS registry ID 110000353796 (U.S. EPA ECHO) Agency record

    Severity 6.1

  21. Nucor Corp Vulcraft Div, Florence

    TRI reporting facility.

    EPA FRS registry ID 110000353741 (U.S. EPA ECHO) Agency record

    Severity 6.1

  22. City Of Johnsonville / East Wwtp, Johnsonville

    NPDES wastewater discharge permit.

    EPA FRS registry ID 110009704631 (U.S. EPA ECHO) Agency record

    Severity 6

  23. Johnson Controls Battery Group Inc, Florence

    Large hazardous waste generator.

    EPA FRS registry ID 110040101653 (U.S. EPA ECHO) Agency record

    Severity 6

  24. Johnson Controls Battery Group Inc, Florence

    NPDES wastewater discharge permit.

    EPA FRS registry ID 110040101653 (U.S. EPA ECHO) Agency record

    Severity 6

  25. Florence City Of Timmonsville Wwtp, Timmonsville

    NPDES wastewater discharge permit.

    EPA FRS registry ID 110064634506 (U.S. EPA ECHO) Agency record

    Severity 6

Correctional facilities

Prisons, jails and corrections operations with an EPA facility record, and the drinking water and wastewater compliance attached to them.

No correctional facility with an EPA record is located in this county.

Discovery / public records

Records to request for Florence County

  • South Carolina state cancer registry

    Cancer incidence counts by census tract or ZIP code, by cancer type and year (de-identified). Any cancer cluster inquiries or investigations in Florence County, and their findings.

  • South Carolina vital statistics office

    Death certificate counts by cause of death and residence tract or ZIP code, and the years behind the mortality measures above.

  • South Carolina health department, environmental epidemiology

    Health consultations or assessments by ATSDR or the state health department covering the county, and any exposure investigations.

  • South Carolina environmental agency and the U.S. EPA regional office

    Compliance history, inspection reports, notices of violation, penalties and enforcement actions for each facility above, cited by EPA FRS registry ID.

  • South Carolina drinking water program

    Violation notices, sampling results and sanitary surveys for the public water systems serving the county, including any system serving a correctional facility.

  • Department of corrections or county sheriff

    Water testing, grievances and environmental health inspections for the correctional facilities listed above.

Each Envyrofax address report includes a printable records request worksheet with the custodian and the exact request wording per finding.

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